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The α6β4 integrin promotes resistance to ferroptosis
Increases in lipid peroxidation can cause ferroptosis, a form of cell death triggered by inhibition of glutathione peroxidase 4 (GPX4), which catalyzes the reduction of lipid peroxides and is a target of ferroptosis inducers, such as erastin. The α6β4 integrin protects adherent epithelial and carcin...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716272/ https://ncbi.nlm.nih.gov/pubmed/28972104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201701136 |
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