Effective immunosuppressive management with belatacept and eculizumab in post-transplant aHUS due to a homozygous deletion of CFHR1/CFHR3 and the presence of CFH antibodies

Atypical haemolytic uraemic syndrome (aHUS) may clinically present as acute renal graft failure resulting from excessive activation of the complement cascade. While mutations of complement-encoding genes predispose for aHUS, it is generally thought to require an additional insult (e.g. drugs) to tri...

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Publicado en:Clin Kidney J
Autores principales: Münch, Johannes, Bachmann, Anette, Grohmann, Maik, Mayer, Christof, Kirschfink, Michael, Lindner, Tom H, Bergmann, Carsten, Halbritter, Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
Materias:
Rare Diseases
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716210/
https://ncbi.nlm.nih.gov/pubmed/29225802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfx053
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