Preclinical drug screen reveals topotecan, actinomycin D, and volasertib as potential new therapeutic candidates for ETMR brain tumor patients

BACKGROUND: Embryonal tumor with multilayered rosettes (ETMR) is a rare and aggressive embryonal brain tumor that solely occurs in infants and young children and has only recently been recognized as a separate brain tumor entity in the World Health Organization classification for CNS tumors. Patient...

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Publicado en:Neuro Oncol
Autores principales: Schmidt, Christin, Schubert, Nil A, Brabetz, Sebastian, Mack, Norman, Schwalm, Benjamin, Chan, Jennifer A, Selt, Florian, Herold-Mende, Christel, Witt, Olaf, Milde, Till, Pfister, Stefan M, Korshunov, Andrey, Kool, Marcel
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
Materias:
Basic and Translational Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716199/
https://ncbi.nlm.nih.gov/pubmed/28482026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox093
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