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Human stem cell–derived astrocytes replicate human prions in a PRNP genotype–dependent manner
Prions are infectious agents that cause neurodegenerative diseases such as Creutzfeldt–Jakob disease (CJD). The absence of a human cell culture model that replicates human prions has hampered prion disease research for decades. In this paper, we show that astrocytes derived from human induced plurip...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716027/ https://ncbi.nlm.nih.gov/pubmed/29141869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161547 |
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