Selective killing of Helicobacter pylori with pH-responsive helix–coil conformation transitionable antimicrobial polypeptides

Current clinical treatment of Helicobacter pylori infection, the main etiological factor in the development of gastritis, gastric ulcers, and gastric carcinoma, requires a combination of at least two antibiotics and one proton pump inhibitor. However, such triple therapy suffers from progressively d...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Xiong, Menghua, Bao, Yan, Xu, Xin, Wang, Hua, Han, Zhiyuan, Wang, Zhiyu, Liu, Yeqing, Huang, Songyin, Song, Ziyuan, Chen, Jinjing, Peek, Richard M., Yin, Lichen, Chen, Lin-Feng, Cheng, Jianjun
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
Physical Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715757/
https://ncbi.nlm.nih.gov/pubmed/29133389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710408114
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