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Insights into functions of the H channel of cytochrome c oxidase from atomistic molecular dynamics simulations

Proton pumping A-type cytochrome c oxidase (CcO) terminates the respiratory chains of mitochondria and many bacteria. Three possible proton transfer pathways (D, K, and H channels) have been identified based on structural, functional, and mutational data. Whereas the D channel provides the route for...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Sharma, Vivek, Jambrina, Pablo G., Kaukonen, Markus, Rosta, Edina, Rich, Peter R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715751/
https://ncbi.nlm.nih.gov/pubmed/29133387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708628114
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