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Neuregulin-1β induces proliferation, survival and paracrine signaling in normal human cardiac ventricular fibroblasts

Neuregulin-1β (NRG-1β) is critical for cardiac development and repair, and recombinant forms are currently being assessed as possible therapeutics for systolic heart failure. We previously demonstrated that recombinant NRG-1β reduces cardiac fibrosis in an animal model of cardiac remodeling and hear...

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Kirabo, Annet, Ryzhov, Sergey, Gupte, Manisha, Sengsayadeth, Seng, Gumina, Richard J., Sawyer, Douglas B., Galindo, Cristi L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715731/
https://ncbi.nlm.nih.gov/pubmed/28263756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.03.001
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