TLR-4 and CD14 Genotypes and Soluble CD14: Could They Predispose to Coronary Atherosclerosis?

Background: Inflammatory mechanisms are key to the pathogenesis of atherosclerosis. Functional polymorphisms of TLR-4, Asp299Gly and Thr399Ile, CD14 promoter area C260T polymorphism and plasma levels of soluble CD14 are studied in subjects with Coronary Artery Disease (CAD). Methods: DNA was obtaine...

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Vydáno v:J Cardiovasc Dev Dis
Hlavní autoři: Konstantinidou, Maria Kalliopi, Goutas, Nikos, Vlachodimitropoulos, Dimitrios, Chaidaroglou, Antigoni, Stefanou, Demetrios, Poumpouridou, Nikoleta, Mastorakou, Renata, Gazouli, Maria, Kyparissopoulos, Dimitrios, Spiliopoulou, Chara
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715697/
https://ncbi.nlm.nih.gov/pubmed/29367560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcdd3010009
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