Synthetic peptides designed to modulate adiponectin assembly improve obesity‐related metabolic disorders

BACKGROUND AND PURPOSE: Adiponectin, an adipokine possessing profound insulin‐sensitizing and anti‐inflammatory properties, is a potent biotherapeutic agent . The trimeric adiponectin subunit assembles into hexameric and functionally important higher molecular weight (HMW) forms, controlled by the e...

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Publicat a:Br J Pharmacol
Autors principals: Hampe, Lutz, Xu, Cheng, Harris, Paul W R, Chen, Jie, Liu, Ming, Middleditch, Martin, Radjainia, Mazdak, Wang, Yu, Mitra, Alok K
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715598/
https://ncbi.nlm.nih.gov/pubmed/28945274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14050
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