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Agonism of free fatty acid receptors 1 and 4 generates peptide YY‐mediated inhibitory responses in mouse colon

BACKGROUND AND PURPOSE: Free fatty acid receptors FFA1 and FFA4 are located on enteroendocrine L cells with the highest gastrointestinal (GI) expression in descending colon. Their activation causes the release of glucagon‐like peptide 1 and peptide YY (PYY) from L cells. Additionally, FFA1 agonism r...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Moodaley, Runisha, Smith, David M, Tough, Iain R, Schindler, Marcus, Cox, Helen M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715575/
https://ncbi.nlm.nih.gov/pubmed/28971469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14054
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