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Beyond symptomatic effects: potential of donepezil as a neuroprotective agent and disease modifier in Alzheimer's disease

Alzheimer's disease (AD) is associated with neurodegenerative changes resulting clinically in progressive cognitive and functional deficits. The only therapies are the cholinesterase inhibitors donepezil, galantamine and rivastigmine and the N‐methyl‐D‐aspartate‐receptor antagonist memantine. D...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Kim, Seung Hyun, Kandiah, Nagaendran, Hsu, Jung‐Lung, Suthisisang, Chuthamanee, Udommongkol, Chesda, Dash, Amitabh
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715569/
https://ncbi.nlm.nih.gov/pubmed/28901528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14030
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