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Inhibitory or excitatory? Optogenetic interrogation of the functional roles of GABAergic interneurons in epileptogenesis

Alteration in the excitatory/inhibitory neuronal balance is believed to be the underlying mechanism of epileptogenesis. Based on this theory, GABAergic interneurons are regarded as the primary inhibitory neurons, whose failure of action permits hyperactivity in the epileptic circuitry. As a conseque...

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Publicat a:J Biomed Sci
Autors principals: Ye, Hui, Kaszuba, Stephanie
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715558/
https://ncbi.nlm.nih.gov/pubmed/29202749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0399-8
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