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Inhibitory or excitatory? Optogenetic interrogation of the functional roles of GABAergic interneurons in epileptogenesis

Alteration in the excitatory/inhibitory neuronal balance is believed to be the underlying mechanism of epileptogenesis. Based on this theory, GABAergic interneurons are regarded as the primary inhibitory neurons, whose failure of action permits hyperactivity in the epileptic circuitry. As a conseque...

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Detalles Bibliográficos
Publicado en:J Biomed Sci
Main Authors: Ye, Hui, Kaszuba, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715558/
https://ncbi.nlm.nih.gov/pubmed/29202749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0399-8
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