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Mitochondrial DNA mutation load in a family with the m.8344A>G point mutation and lipomas: a case study

Studies have shown that difference in mtDNA mutation load among tissues is a result of postnatal modification. We present five family members with the m.8344A>G with variable phenotypes but uniform intrapersonal distribution of mutation load, indicating that there is no postnatal modification of...

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Bibliografiske detaljer
Udgivet i:Clin Case Rep
Main Authors: Jeppesen, Tina Dysgaard, Al‐Hashimi, Noor, Duno, Morten, Wibrand, Flemming, Andersen, Grete, Vissing, John
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715413/
https://ncbi.nlm.nih.gov/pubmed/29225851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.1096
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