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Efficient and flexible implementation of Langevin simulation for gene burst production

Gene expression involves bursts of production of both mRNA and protein, and the fluctuations in their number are increased due to such bursts. The Langevin equation is an efficient and versatile means to simulate such number fluctuation. However, how to include these mRNA and protein bursts in the L...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yan, Ching-Cher Sanders, Chepyala, Surendhar Reddy, Yen, Chao-Ming, Hsu, Chao-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715166/
https://ncbi.nlm.nih.gov/pubmed/29203832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16835-y
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