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Various N-glycoforms differentially upregulate E-NTPDase activity of the NTPDase3/CD39L3 ecto-enzymatic domain

The GDA1/CD39 ecto-nucleoside triphosphate diphosphosphohydrolase (E-NTPDase) superfamily is a group of eight heavily glycosylated ecto-enzymes that hydrolyze extracellular nucleosides di- and tri-phosphates in the presence of divalent cations, to generate the monophosphate derivatives. This catalyt...

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Veröffentlicht in:Purinergic Signal
Hauptverfasser: Zhong, Alexander H., Gordon Jiang, Z., Cummings, Richard D., Robson, Simon C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714850/
https://ncbi.nlm.nih.gov/pubmed/28956227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-017-9587-y
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