Mitochondrial DNA content is associated with ploidy status, maternal age, and oocyte maturation methods in mouse blastocysts

PURPOSE: It was reported that mitochondrial DNA (mtDNA) was significantly increased in aneuploid human embryos compared to euploid embryos and was also associated with maternal age. In this study, we further established the mouse model of mtDNA quantitation in reproductive samples based on whole-gen...

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Dettagli Bibliografici
Pubblicato in:J Assist Reprod Genet
Autori principali: Tao, Xin, Landis, Jessica N., Krisher, Rebecca L., Duncan, Francesca E., Silva, Elena, Lonczak, Agnieszka, Scott, Richard T., Zhan, Yiping, Chu, Tinchun, Treff, Nathan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2017
Soggetti:
Embryo Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714829/
https://ncbi.nlm.nih.gov/pubmed/29063991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-017-1070-8
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