CoQ10 increases mitochondrial mass and polarization, ATP and Oct4 potency levels, and bovine oocyte MII during IVM while decreasing AMPK activity and oocyte death

PURPOSE: We tested whether mitochondrial electron transport chain electron carrier coenzyme Q10 (CoQ10) increases ATP during bovine IVM and increases %M2 oocytes, mitochondrial polarization/mass, and Oct4, and decreases pAMPK and oocyte death. METHODS: Bovine oocytes were aspirated from ovaries and...

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Bibliografiske detaljer
Udgivet i:J Assist Reprod Genet
Main Authors: Abdulhasan, M. K., Li, Q., Dai, J., Abu-Soud, H. M., Puscheck, E. E., Rappolee, D. A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2017
Fag:
Gamete Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714820/
https://ncbi.nlm.nih.gov/pubmed/28900834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-017-1027-y
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