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Long non-coding RNA HOTAIR enhances angiogenesis by induction of VEGFA expression in glioma cells and transmission to endothelial cells via glioma cell derived-extracellular vesicles

Gliomas are one the most prevalent malignant carcinomas of the central nervous system, and angiogenesis plays a critical role in the progression of these blood vessel-rich tumors. HOTAIR, a long non-coding RNA (lncRNA), acts as an oncogene in gliomas; however, its role in glioma angiogenesis remains...

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Publicado en:Am J Transl Res
Autores principales: Ma, Xin, Li, Zhaohui, Li, Ting, Zhu, Linwensi, Li, Zhenshengnan, Tian, Nan
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714785/
https://ncbi.nlm.nih.gov/pubmed/29218099
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