Evaluation of the role of downregulation of SNF5/INI1 core subunit of SWI/SNF complex in clear cell renal cell carcinoma development

Clear cell renal cell carcinoma (ccRCC) is characterized by stabilization of hypoxia-inducible factor (HIF1), and mutations in von Hippel-Lindau (VHL) gene. Additionally, in about 40% of ccRCC cases the mutation in PBRM1 (POLYBROMO1) gene coding for a non-core subunit of SWI/SNF chromatin remodeling...

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Vydáno v:Am J Cancer Res
Hlavní autoři: Sarnowska, Elzbieta, Szymanski, Michal, Rusetska, Nataliia, Ligaj, Marcin, Jancewicz, Iga, Cwiek, Pawel, Skrodzka, Marta, Leszczynski, Marcin, Szarkowska, Joanna, Chrzan, Alicja, Stachowiak, Malgorzata, Steciuk, Jaroslaw, Maassen, Anna, Galek, Lech, Demkow, Tomasz, Siedlecki, Janusz A, Sarnowski, Tomasz J
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714755/
https://ncbi.nlm.nih.gov/pubmed/29218250
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