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Link Between Affinity and Cu(II) Binding Sites to Amyloid-β Peptides Evaluated by a New Water-Soluble UV-Visible Ratiometric Dye with a Moderate Cu(II) Affinity

Being able to easily determine the Cu(II) affinity for biomolecules of moderate affinity is important. Such biomolecules include amyloidogenic peptides, such as the well-known amyloid-β peptide involved in Alzheimer’s disease. Here, we report the synthesis of a new water soluble ratiometric Cu(II) d...

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Publicado en:Anal Chem
Main Authors: Conte-Daban, Amandine, Borghesani, Valentina, Sayen, Stéphanie, Guillon, Emmanuel, Journaux, Yves, Gontard, Geoffrey, Lisnard, Laurent, Hureau, Christelle
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714188/
https://ncbi.nlm.nih.gov/pubmed/28208266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b04979
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