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Computational construction of 3D chromatin ensembles and prediction of functional interactions of alpha-globin locus from 5C data
Conformation capture technologies measure frequencies of interactions between chromatin regions. However, understanding gene-regulation require knowledge of detailed spatial structures of heterogeneous chromatin in cells. Here we describe the nC-SAC (n-Constrained-Self Avoiding Chromatin) method tha...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5714131/ https://ncbi.nlm.nih.gov/pubmed/28981716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx784 |
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