Collateral Damage Intended—Cancer-Associated Fibroblasts and Vasculature Are Potential Targets in Cancer Therapy

After oncogenic transformation, tumor cells rewire their metabolism to obtain sufficient energy and biochemical building blocks for cell proliferation, even under hypoxic conditions. Glucose and glutamine become their major limiting nutritional demands. Instead of being autonomous, tumor cells chang...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Cavaco, Ana, Rezaei, Maryam, Niland, Stephan, Eble, Johannes A.
Format: Artigo
Language:Inglês
Published: MDPI 2017
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713324/
https://ncbi.nlm.nih.gov/pubmed/29112161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18112355
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