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Haplotypes inside the beta-globin gene: use as new biomarkers for beta-thalassemia prenatal diagnosis in north of Iran

BACKGROUND: Beta-thalassemia is common in the Mediterranean area as well as the Middle East and India. Official report in Iran revealed the average prevalence rate of carriers about 4%. More than 20 restriction fragment length polymorphisms (RFLPs) are known in the beta-globin gene cluster and used...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Hashemi-Soteh, Mohammad Bagher, Mousavi, Seyed Saeed, Tafazoli, Alireza
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713070/
https://ncbi.nlm.nih.gov/pubmed/29202846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0396-y
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