Quantitative time-course metabolomics in human red blood cells reveal the temperature dependence of human metabolic networks

The temperature dependence of biological processes has been studied at the levels of individual biochemical reactions and organism physiology (e.g. basal metabolic rates) but has not been examined at the metabolic network level. Here, we used a systems biology approach to characterize the temperatur...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Yurkovich, James T., Zielinski, Daniel C., Yang, Laurence, Paglia, Giuseppe, Rolfsson, Ottar, Sigurjónsson, Ólafur E., Broddrick, Jared T., Bordbar, Aarash, Wichuk, Kristine, Brynjólfsson, Sigurður, Palsson, Sirus, Gudmundsson, Sveinn, Palsson, Bernhard O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712598/
https://ncbi.nlm.nih.gov/pubmed/29030425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.804914
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