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Targeted Base Editing via RNA-Guided Cytidine Deaminases in Xenopus laevis Embryos
Genome editing using programmable nucleases such as CRISPR/Cas9 or Cpf1 has emerged as powerful tools for gene knock-out or knock-in in various organisms. While most genetic diseases are caused by point mutations, these genome-editing approaches are inefficient in inducing single-nucleotide substitu...
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| Publicado en: | Mol Cells |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Korean Society for Molecular and Cellular Biology
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5712511/ https://ncbi.nlm.nih.gov/pubmed/29179261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2017.0262 |
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