Discrimination of germline EGFR T790M mutations in plasma cell-free DNA allows study of prevalence across 31,414 cancer patients

PURPOSE: Plasma cell-free DNA (cfDNA) analysis is increasingly used clinically for cancer genotyping, but may lead to incidental identification of germline risk alleles. We studied EGFR T790M mutations in non-small cell lung cancer (NSCLC) toward the aim of discriminating germline and cancer-derived...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Hu, Yuebi, Alden, Ryan S., Odegaard, Justin I., Fairclough, Stephen R., Chen, Ruthia, Heng, Jennifer, Feeney, Nora, Nagy, Rebecca J., Shah, Jayshree, Ulrich, Bryan, Gutierrez, Martin, Lanman, Richard B., Garber, Judy E., Paweletz, Cloud P., Oxnard, Geoffrey R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712272/
https://ncbi.nlm.nih.gov/pubmed/28947568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1745
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge