A novel image-based high throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease

Glycogen storage disorders (GSDs) are caused by excessive accumulation of glycogen. Some GSDs (Adult Polyglucosan Body Disease (APBD), Tarui and Lafora diseases) are caused by intracellular accumulation of insoluble inclusions, called polyglucosan bodies (PB), which are chiefly composed of malconstr...

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Foilsithe in:Biochem J
Main Authors: Solmesky, Leonardo J., Khazanov, Netaly, Senderowitz, Hanoch, Wang, Peixiang, Minassian, Berge A., Ferreira, Igor M., Yue, Wyatt W., Lossos, Alexander, Weil, Miguel, Kakhlon, Or
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712202/
https://ncbi.nlm.nih.gov/pubmed/28827282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170469
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