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Histone profiling reveals the H1.3 histone variant as a prognostic biomarker for pancreatic ductal adenocarcinoma

BACKGROUND: Epigenetic alterations have been recognized as important contributors to the pathogenesis of PDAC. However, the role of histone variants in pancreatic tumor progression is still not completely understood. The aim of this study was to explore the expression and prognostic significance of...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Bauden, Monika, Kristl, Theresa, Sasor, Agata, Andersson, Bodil, Marko-Varga, György, Andersson, Roland, Ansari, Daniel
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712195/
https://ncbi.nlm.nih.gov/pubmed/29197353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3834-z
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