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Histone profiling reveals the H1.3 histone variant as a prognostic biomarker for pancreatic ductal adenocarcinoma

BACKGROUND: Epigenetic alterations have been recognized as important contributors to the pathogenesis of PDAC. However, the role of histone variants in pancreatic tumor progression is still not completely understood. The aim of this study was to explore the expression and prognostic significance of...

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Publicat a:BMC Cancer
Autors principals: Bauden, Monika, Kristl, Theresa, Sasor, Agata, Andersson, Bodil, Marko-Varga, György, Andersson, Roland, Ansari, Daniel
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712195/
https://ncbi.nlm.nih.gov/pubmed/29197353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3834-z
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