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The repeat region of cortactin is intrinsically disordered in solution
The multi-domain protein, cortactin, contains a 37-residue repeating motif that binds to actin filaments. This cortactin repeat region comprises 6½ similar copies of the motif and binds actin filaments. To better understand this region of cortactin, and its fold, we conducted extensive biophysical a...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5711941/ https://ncbi.nlm.nih.gov/pubmed/29196701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16959-1 |
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