Sequestosome1/p62 protects mouse embryonic fibroblasts against low-dose methylercury-induced cytotoxicity and is involved in clearance of ubiquitinated proteins

Methylmercury (MeHg) is a widely distributed environmental pollutant that causes a series of cytotoxic effects. However, molecular mechanisms underlying MeHg toxicity are not fully understood. Here, we report that sequestosome1/p62 protects mouse embryonic fibroblasts (MEFs) against low-dose MeHg cy...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Takanezawa, Yasukazu, Nakamura, Ryosuke, Harada, Ryohei, Sone, Yuka, Uraguchi, Shimpei, Kiyono, Masako
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711938/
https://ncbi.nlm.nih.gov/pubmed/29196648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17112-8
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