Single Dose of Consensus Hemagglutinin-Based Virus-Like Particles Vaccine Protects Chickens against Divergent H5 Subtype Influenza Viruses

The H5 subtype highly pathogenic avian influenza (HPAI) virus is one of the greatest threats to global poultry industry. To develop broadly protective H5 subunit vaccine, a recombinant consensus HA sequence (rHA) was constructed and expressed in virus-like particles (rHA VLPs) in the baculovirus-ins...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Wu, Peipei, Lu, Jihu, Zhang, Xuehua, Mei, Mei, Feng, Lei, Peng, Daxin, Hou, Jibo, Kang, Sang-Moo, Liu, Xiufan, Tang, Yinghua
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711813/
https://ncbi.nlm.nih.gov/pubmed/29230222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01649
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