Single Dose of Consensus Hemagglutinin-Based Virus-Like Particles Vaccine Protects Chickens against Divergent H5 Subtype Influenza Viruses

The H5 subtype highly pathogenic avian influenza (HPAI) virus is one of the greatest threats to global poultry industry. To develop broadly protective H5 subunit vaccine, a recombinant consensus HA sequence (rHA) was constructed and expressed in virus-like particles (rHA VLPs) in the baculovirus-ins...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wu, Peipei, Lu, Jihu, Zhang, Xuehua, Mei, Mei, Feng, Lei, Peng, Daxin, Hou, Jibo, Kang, Sang-Moo, Liu, Xiufan, Tang, Yinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711813/
https://ncbi.nlm.nih.gov/pubmed/29230222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01649
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