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Evaluation of Aggregated Ag85B Antigen for Its Biophysical Properties, Immunogenicity, and Vaccination Potential in a Murine Model of Tuberculosis Infection

Protein aggregates have been reported to act as a reservoir that can release biologically active, native form of precursor protein. Keeping this fact into consideration, it is tempting to exploit protein aggregate-based antigen delivery system as a functional vaccine to expand desirable immunologica...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ahmad, Faraz, Zubair, Swaleha, Gupta, Pushpa, Gupta, Umesh Datta, Patel, Rakesh, Owais, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711810/
https://ncbi.nlm.nih.gov/pubmed/29230211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01608
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