LRSim: A Linked-Reads Simulator Generating Insights for Better Genome Partitioning

Linked-read sequencing, using highly-multiplexed genome partitioning and barcoding, can span hundreds of kilobases to improve de novo assembly, haplotype phasing, and other applications. Based on our analysis of 14 datasets, we introduce LRSim that simulates linked-reads by emulating the library pre...

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Dades bibliogràfiques
Publicat a:Comput Struct Biotechnol J
Autors principals: Luo, Ruibang, Sedlazeck, Fritz J., Darby, Charlotte A., Kelly, Stephen M., Schatz, Michael C.
Format: Artigo
Idioma:Inglês
Publicat: Research Network of Computational and Structural Biotechnology 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711661/
https://ncbi.nlm.nih.gov/pubmed/29213995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2017.10.002
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