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Kanamycin damages early postnatal, but not adult spiral ganglion neurons

Although aminoglycoside antibiotics such as kanamycin are widely used clinically to treat life threatening bacterial infections, ototoxicity remains a significant dose-limiting side effect. The prevailing view is that the hair cells are the primary ototoxic target of aminoglycosides and that spiral...

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Detalhes bibliográficos
Publicado no:Neurotox Res
Main Authors: Gao, Kelei, Ding, Dalian, Sun, Hong, Roth, Jerome, Salvi, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711550/
https://ncbi.nlm.nih.gov/pubmed/28656549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-017-9773-2
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