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The Aspergillus fumigatus farnesyltransferase β-subunit, RamA, mediates growth, virulence, and antifungal susceptibility

Post-translational prenylation mechanisms, including farnesylation and geranylgeranylation, mediate both subcellular localization and protein-protein interaction in eukaryotes. The prenyltransferase complex is an αβ heterodimer in which the essential α-subunit is common to both the farnesyltransfera...

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Publicat a:Virulence
Autors principals: Norton, Tiffany S., Al Abdallah, Qusai, Hill, Amy M., Lovingood, Rachel V., Fortwendel, Jarrod R.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711395/
https://ncbi.nlm.nih.gov/pubmed/28489963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2017.1328343
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