Metabomatching: Using genetic association to identify metabolites in proton NMR spectroscopy

A metabolome-wide genome-wide association study (mGWAS) aims to discover the effects of genetic variants on metabolome phenotypes. Most mGWASes use as phenotypes concentrations of limited sets of metabolites that can be identified and quantified from spectral information. In contrast, in an untarget...

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Опубликовано в: :PLoS Comput Biol
Главные авторы: Rueedi, Rico, Mallol, Roger, Raffler, Johannes, Lamparter, David, Friedrich, Nele, Vollenweider, Peter, Waeber, Gérard, Kastenmüller, Gabi, Kutalik, Zoltán, Bergmann, Sven
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711027/
https://ncbi.nlm.nih.gov/pubmed/29194434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005839
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