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Metabomatching: Using genetic association to identify metabolites in proton NMR spectroscopy

A metabolome-wide genome-wide association study (mGWAS) aims to discover the effects of genetic variants on metabolome phenotypes. Most mGWASes use as phenotypes concentrations of limited sets of metabolites that can be identified and quantified from spectral information. In contrast, in an untarget...

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Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Rueedi, Rico, Mallol, Roger, Raffler, Johannes, Lamparter, David, Friedrich, Nele, Vollenweider, Peter, Waeber, Gérard, Kastenmüller, Gabi, Kutalik, Zoltán, Bergmann, Sven
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711027/
https://ncbi.nlm.nih.gov/pubmed/29194434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005839
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