Carbon ion irradiation abrogates Lin28B-induced X-ray resistance in melanoma cells

The Lin28/let-7 axis plays an important role in tumor initiation and developmental processes. Lin28B is upregulated in a variety of cancers, and its overexpression enhances cancer cell proliferation and radioresistance through the suppression of let-7 micro RNA expression. In this study, we investig...

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Bibliografiske detaljer
Udgivet i:J Radiat Res
Main Authors: Park, Seong-Joon, Heo, Kyu, Choi, Chulwon, Yang, Kwangmo, Adachi, Akiko, Okada, Hiroko, Yoshida, Yukari, Ohno, Tatsuya, Nakano, Takashi, Takahashi, Akihisa
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710593/
https://ncbi.nlm.nih.gov/pubmed/28482074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrx022
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