Safety of Converting From Tetrabenazine to Deutetrabenazine for the Treatment of Chorea

IMPORTANCE: Tetrabenazine is efficacious for chorea control; however, tolerability concerns exist. Deutetrabenazine, a novel molecule that reduces chorea, was well tolerated in a double-blind, placebo-controlled study. OBJECTIVES: To evaluate the safety and explore the efficacy of conversion from te...

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Vydáno v:JAMA Neurol
Hlavní autoři: Frank, Samuel, Stamler, David, Kayson, Elise, Claassen, Daniel O., Colcher, Amy, Davis, Charles, Duker, Andrew, Eberly, Shirley, Elmer, Lawrence, Furr-Stimming, Erin, Gudesblatt, Mark, Hunter, Christine, Jankovic, Joseph, Kostyk, Sandra K., Kumar, Rajeev, Loy, Clement, Mallonee, William, Oakes, David, Scott, Burton L., Sung, Victor, Goldstein, Jody, Vaughan, Christina, Testa, Claudia M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2017
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710322/
https://ncbi.nlm.nih.gov/pubmed/28692723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.1352
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