Oral Tyrosine Kinase Inhibitor for Neovascular Age-Related Macular Degeneration: A Phase 1 Dose-Escalation Study

IMPORTANCE: An oral treatment for neovascular age-related macular degeneration would be less burdensome than repeated intravitreous injections. X-82 is an oral tyrosine kinase inhibitor active against vascular endothelial growth factor (VEGF) and platelet-derived growth factor. OBJECTIVE: To underta...

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Detalhes bibliográficos
Publicado no:JAMA Ophthalmol
Main Authors: Jackson, Timothy L., Boyer, David, Brown, David M., Chaudhry, Nauman, Elman, Michael, Liang, Chris, O’Shaughnessy, Denis, Parsons, Edward C., Patel, Sunil, Slakter, Jason S., Rosenfeld, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710207/
https://ncbi.nlm.nih.gov/pubmed/28570723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2017.1571
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