Comparing Plasma Phospho Tau, Total Tau, and Phospho Tau–Total Tau Ratio as Acute and Chronic Traumatic Brain Injury Biomarkers

IMPORTANCE: Annually in the United States, at least 3.5 million people seek medical attention for traumatic brain injury (TBI). The development of therapies for TBI is limited by the absence of diagnostic and prognostic biomarkers. Microtubule-associated protein tau is an axonal phosphoprotein. To d...

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Publicat a:JAMA Neurol
Autors principals: Rubenstein, Richard, Chang, Binggong, Yue, John K., Chiu, Allen, Winkler, Ethan A., Puccio, Ava M., Diaz-Arrastia, Ramon, Yuh, Esther L., Mukherjee, Pratik, Valadka, Alex B., Gordon, Wayne A., Okonkwo, David O., Davies, Peter, Agarwal, Sanjeev, Lin, Fan, Sarkis, George, Yadikar, Hamad, Yang, Zhihui, Manley, Geoffrey T., Wang, Kevin K. W., Cooper, Shelly R., Dams-O’Connor, Kristen, Borrasso, Allison J., Inoue, Tomoo, Maas, Andrew I. R., Menon, David K., Schnyer, David M., Vassar, Mary J.
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2017
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710183/
https://ncbi.nlm.nih.gov/pubmed/28738126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.0655
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