Comparing Plasma Phospho Tau, Total Tau, and Phospho Tau–Total Tau Ratio as Acute and Chronic Traumatic Brain Injury Biomarkers

IMPORTANCE: Annually in the United States, at least 3.5 million people seek medical attention for traumatic brain injury (TBI). The development of therapies for TBI is limited by the absence of diagnostic and prognostic biomarkers. Microtubule-associated protein tau is an axonal phosphoprotein. To d...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Rubenstein, Richard, Chang, Binggong, Yue, John K., Chiu, Allen, Winkler, Ethan A., Puccio, Ava M., Diaz-Arrastia, Ramon, Yuh, Esther L., Mukherjee, Pratik, Valadka, Alex B., Gordon, Wayne A., Okonkwo, David O., Davies, Peter, Agarwal, Sanjeev, Lin, Fan, Sarkis, George, Yadikar, Hamad, Yang, Zhihui, Manley, Geoffrey T., Wang, Kevin K. W., Cooper, Shelly R., Dams-O’Connor, Kristen, Borrasso, Allison J., Inoue, Tomoo, Maas, Andrew I. R., Menon, David K., Schnyer, David M., Vassar, Mary J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710183/
https://ncbi.nlm.nih.gov/pubmed/28738126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.0655
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