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The combination therapy of salinomycin and gefitinib using poly(d,l-lactic-co-glycolic acid)-poly(ethylene glycol) nanoparticles for targeting both lung cancer stem cells and cancer cells

PURPOSE: Lung cancer (LC) is the leading cause of cancer death worldwide. Evidences suggest that both LC cancer stem cells (CSCs) and cancer cells are supposed to be eliminated to achieve superior treatment effect against LC. Salinomycin could eradiate CSCs in various types of cancers, and gefitinib...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Zhang, Yu, Zhang, Qi, Sun, Jing, Liu, Huijie, Li, Qingfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709995/
https://ncbi.nlm.nih.gov/pubmed/29225473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S141083
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