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Decontaminating eukaryotic genome assemblies with machine learning

BACKGROUND: High-throughput sequencing has made it theoretically possible to obtain high-quality de novo assembled genome sequences but in practice DNA extracts are often contaminated with sequences from other organisms. Currently, there are few existing methods for rigorously decontaminating eukary...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Fierst, Janna L., Murdock, Duncan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709863/
https://ncbi.nlm.nih.gov/pubmed/29191179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1941-0
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