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Weighted likelihood inference of genomic autozygosity patterns in dense genotype data

BACKGROUND: Genomic regions of autozygosity (ROA) arise when an individual is homozygous for haplotypes inherited identical-by-descent from ancestors shared by both parents. Over the past decade, they have gained importance for understanding evolutionary history and the genetic basis of complex dise...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Blant, Alexandra, Kwong, Michelle, Szpiech, Zachary A., Pemberton, Trevor J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709839/
https://ncbi.nlm.nih.gov/pubmed/29191164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4312-3
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