Prognostic implications of abnormalities of chromosome 13 and the presence of multiple cytogenetic high-risk abnormalities in newly diagnosed multiple myeloma

Fluorescence in situ hybridization evaluation is essential for initial risk stratification in multiple myeloma. While the presence of specific cytogenetic high-risk abnormalities (HRA) is known to confer a poor prognosis, less is known about the cumulative effect of multiple HRA. We studied 1181 pat...

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Veröffentlicht in:Blood Cancer J
Hauptverfasser: Binder, M, Rajkumar, S V, Ketterling, R P, Greipp, P T, Dispenzieri, A, Lacy, M Q, Gertz, M A, Buadi, F K, Hayman, S R, Hwa, Y L, Zeldenrust, S R, Lust, J A, Russell, S J, Leung, N, Kapoor, P, Go, R S, Gonsalves, W I, Kyle, R A, Kumar, S K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709752/
https://ncbi.nlm.nih.gov/pubmed/28862698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2017.83
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