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Role of Brf1 interaction with ERα, and significance of its overexpression, in human breast cancer

TFIIB‐related factor 1 (Brf1) modulates the transcription of RNA Pol III genes (polymerase‐dependent genes). Upregulation of Pol III genes enhances tRNA and 5S RNA production and increases the translational capacity of cells to promote cell transformation and tumor development. However, the signific...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Fang, Zeng, Yi, Yunfeng, Shi, Ganggang, Li, Songqi, Chen, Songlin, Lin, Ying, Li, Zhi, He, Zhimin, Li, Wen, Zhong, Shuping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709663/
https://ncbi.nlm.nih.gov/pubmed/28972307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12141
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