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MicroRNA-21 regulates Osteogenic Differentiation of Periodontal Ligament Stem Cells by targeting Smad5

Human periodontal ligament stem cells (hPDLSCs) are mesenchymal stem cells (MSCs) derived from dental and craniofacial tissues that exhibit high potential for differentiation into osteoblasts. Recently, microRNAs (miRNAs) have been established to play important roles in MSC osteogenesis. In the curr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wei, Fulan, Yang, Shuangyan, Guo, Qingyuan, Zhang, Xin, Ren, Dapeng, Lv, Tao, Xu, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709498/
https://ncbi.nlm.nih.gov/pubmed/29192241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16720-8
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