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MicroRNA-21 regulates Osteogenic Differentiation of Periodontal Ligament Stem Cells by targeting Smad5

Human periodontal ligament stem cells (hPDLSCs) are mesenchymal stem cells (MSCs) derived from dental and craniofacial tissues that exhibit high potential for differentiation into osteoblasts. Recently, microRNAs (miRNAs) have been established to play important roles in MSC osteogenesis. In the curr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Wei, Fulan, Yang, Shuangyan, Guo, Qingyuan, Zhang, Xin, Ren, Dapeng, Lv, Tao, Xu, Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709498/
https://ncbi.nlm.nih.gov/pubmed/29192241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16720-8
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