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Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes

Cell membranes are crowded and complex environments. To investigate the effect of protein-lipid interactions on dynamic organization in mammalian cell membranes, we have performed coarse-grained molecular dynamics simulations containing >100 copies of an inwardly rectifying potassium (Kir) channe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Duncan, Anna L., Reddy, Tyler, Koldsø, Heidi, Hélie, Jean, Fowler, Philip W., Chavent, Matthieu, Sansom, Mark S. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709381/
https://ncbi.nlm.nih.gov/pubmed/29192147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16865-6
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