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PGC-1alpha levels correlate with survival in patients with stage III NSCLC and may define a new biomarker to metabolism-targeted therapy

Lung cancer remains the leading cause of cancer-related death worldwide, with one-third diagnosed with locally advanced (stage III) disease. Preoperative induction chemo-radiotherapy is key for the treatment of these patients, however conventional cisplatin based approaches has apparently reached a...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Cruz-Bermúdez, Alberto, Vicente-Blanco, Ramiro J., Laza-Briviesca, Raquel, García-Grande, Aránzazu, Laine-Menéndez, Sara, Gutiérrez, Lourdes, Calvo, Virginia, Romero, Atocha, Martín-Acosta, Paloma, García, José Miguel, Provencio, Mariano
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709355/
https://ncbi.nlm.nih.gov/pubmed/29192176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17009-6
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