Stent-based delivery of adeno-associated viral vectors with sustained vascular transduction and iNOS-mediated inhibition of in-stent restenosis

In-stent restenosis remains an important clinical problem in the era of drug eluting stents. Development of clinical gene therapy protocols for the prevention and treatment of in-stent restenosis is hampered by the lack of adequate local delivery systems. Herein we describe a novel stent-based gene...

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Publicado en:Gene Ther
Autores principales: Fishbein, Ilia, Guerrero, David T., Alferiev, Ivan S., Foster, Jonathan B., Minutolo, Nicholas G., Chorny, Michael, Mas Monteys, Alejandro, Driesbaugh, Kathryn H., Nagaswami, Chandrasekaran, Levy, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709213/
https://ncbi.nlm.nih.gov/pubmed/28832561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2017.82
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