Cross-sectional and longitudinal small animal PET shows pre and post-synaptic striatal dopaminergic deficits in an animal model of HIV

INTRODUCTION: In vivo imaging biomarkers of various HIV neuropathologies, including dopaminergic dysfunction, are still lacking. Towards developing dopaminergic biomarkers of brain involvement in HIV, we assessed the pre and postsynaptic components of the dopaminergic system in the HIV-1 transgenic...

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Publicado no:Nucl Med Biol
Main Authors: Sinharay, Sanhita, Lee, Dianne, Shah, Swati, Muthusamy, Siva, Papadakis, Georgios Z., Zhang, Xiang, Maric, Dragan, Reid, William C., Hammoud, Dima A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709197/
https://ncbi.nlm.nih.gov/pubmed/29031113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2017.08.004
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