Cross-sectional and longitudinal small animal PET shows pre and post-synaptic striatal dopaminergic deficits in an animal model of HIV

INTRODUCTION: In vivo imaging biomarkers of various HIV neuropathologies, including dopaminergic dysfunction, are still lacking. Towards developing dopaminergic biomarkers of brain involvement in HIV, we assessed the pre and postsynaptic components of the dopaminergic system in the HIV-1 transgenic...

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Publicado en:Nucl Med Biol
Autores principales: Sinharay, Sanhita, Lee, Dianne, Shah, Swati, Muthusamy, Siva, Papadakis, Georgios Z., Zhang, Xiang, Maric, Dragan, Reid, William C., Hammoud, Dima A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709197/
https://ncbi.nlm.nih.gov/pubmed/29031113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2017.08.004
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